What Causes a Leaky Gut?

Intestinal hyperpermeability, commonly called Leaky Gut Syndrome, is when the gut’s protective mucosal barrier loses its effectiveness, which allows bacteria, toxins, and unwanted molecules to “leak” into the bloodstream. In this episode of the Thorne Podcast, Dr. Frank Lipman and Dr. Robert Rountree discuss the symptoms of a leaky gut and the techniques for keeping your gut health on track.
During this episode, you’ll learn about:
Increased intestinal permeability [2:50]
New research on intestinal permeability and gut barrier [3:40]
Leaky gut misunderstandings [5:05]


Occurring at microscopic level [5:52]
Leaky Gut and small intestine [6:48]
Endotoxins [7:16]


Leaky gut, obesity, and fatty liver [8:13]
The gut and the body’s inflammatory response [8:41]
Improving the functioning of the gut wall [9:00]
Modern life and overprocessed foods and your gut [9:40]


Medical journals on intestinal permeability [10:28]
Altered microbiome causing leaky gut? [11:31]
Bacteriophages and your gut [12:11]
Achieving gut balance [13:10]
Yeast strains and the gut [14:10]
Fungi [14:40]


Overgrowth and leaky gut [15:00]
Alcohol, anti-inflammatory drugs, and leaky gut [16:21]
High-sugar and high-carb diets [17:12]
Questions from the community [18:47]
Why is leaky gut not more commonly discussed? [18:56]
The name leaky gut [19:00]
Using more technical terms to describe leaky gut [19:20]
Introduce the research on intestinal permeability [19:40]
Alessio Fasano [20:08]
Gluten and leaky gut [20:20]


Testing gluten sensitivity [20:03]
Anti-gliadin antibodies [21:06]
Other proteins in gluten [22:14]


How to tell if I have leaky gut [22:35]
Bloating, gas, irregular bowel movements [22:45]
Joint pain and skin rashes [23:23]


L-glutamine supplements and gut health [24:48]
Other supplements for gut health [25:52]
Peptides and gut health [27:00]



 
Resources to topics mentioned in this episode:
Are You an Athlete Who Suffers From Leaky Gut?
Bugs 101: Probiotics, Prebiotics, and the Microbiome
Body Basics: Understanding How the Gut Acts as a Protective Barrier
Research Extracts: Medication’s Impact on Microbiome | Blueberry Juice For Attention | Gut-Sleep Connection
Formula SF722 — The Go-To Supplement for GI Microbial Balance*


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* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.