Alpha-1 antitrypsin deficiency | the most common genetic cause for paediatric liver transplants

Alpha-1 antitrypsin (A1AT) deficiency is a genetic disorder affecting predominantly the lungs and liver. Although it is considered uncommon, there is some evidence to suggest it is under recognised and under diagnosed. A1AT itself is a protease inhibitor that helps protect the lung and other tissues.  Liver disease is more likely to be the predominant presenting feature in kids, but many people with A1AT enter adulthood without a diagnosis.    Links and resources: Follow us on Instagram @yourekiddingrightdoctors Facebook: https://www.facebook.com/yourekiddingrightpod-107273607638323/ Our email is yourekiddingrightpod@gmail.com Make sure you hit SUBSCRIBE/FOLLOW so you don’t miss out on any pearls of wisdom and RATE if you can to help other people find us! (This isn’t individual medical advice, please use your own clinical judgement and local guidelines when caring for your patients)