S1.E3: Simon, Garfunkel and the Art of Building N-Aryl Piperidines

For our 3rd course we serve up another #MerckChemistry duo, Libby Hennessy (aka Simon) and Aaron Sather (aka Garfunkel) who join us to discuss their discovery of a new way to access N-(hetero)aryl piperidines. We'll discover how to convince your grandma why piperidines are so important to drug discovery and learn how chemistry advances are made at the interface of Process and Medicinal Chemistry at Merck. We'll also dive into the Merck Future Talents program which brings in interns to come work with us. Lastly, Dani and LC probe Libby & Aaron on which superpower would take this chemistry to the next level (or not) .... Listen to find out!
Read the paper we discussed today here:
A Modular and Diastereoselective 5 + 1 Cyclization Approach to N-(Hetero)Aryl Piperidines
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