19. Negative controls are important: a story (mini-series: reading-12)

There are many reasons why life-science experiments do not work well. Today, I will tell you a real story about an experiment. It is an experiment that did not go well. We will explore the problem that researchers encountered. In the following episodes), we will discuss how they identified the problem, and how they solved the problem. The story will help us understand the importance of negative controls, especially how to design them for the experiments, and how to use them for trouble-shooting problematic experiments.   This is Part 12 of the reading mini-series "Let’s read a paper written by Nobel Prize Laureates, 2023."    (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)