Choosing an absorption model (Ep. 24)

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Today’s show discussed approaches for modeling absorption profiles. I discussed the rationale behind modeling absorption and then described some common models. These included first-order absorption, zero-order absorption, transit compartments, distributed delay, Weibull, and zero/first order absorption. I also provided my recommendations on how to model absorption.

Links discussed in the show:

Distributed delay modeling in PK and PD
Modeling biphasic formulation of methylphenidate
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Choosing an absorption model (Ep. 24)

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Clinical Pharmacology Podcast with Nathan Teuscher
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