Nuances of NCA (Ep. 5)
Release Date:
In this episode, I discuss some nuances of non-compartmental analysis or NCA. I am going to focus on three separate parameters: Cmax, AUC, and the terminal elimination rate constant. These three are the most commonly used parameters to describe drug exposure. I’ll discuss the basic methodology for each and then discuss challenges that may arise when you are performing an analysis.
Links discussed in the show:
Images mentioned in the podcast
Derivation of logarithmic AUC
Calculating the elimination rate constant
You can connect with me on LinkedIn and send me a message
Send me a message
Sign up for my newsletter
Copyright Teuscher Solutions LLC
All Rights Reserved
Nuances of NCA (Ep. 5)