Estimands for Repeated Continuous Outcomes

How do we define estimates effectively?
What challenges arise in estimating treatment policy, particularly in the context of missing data and patient discontinuation?
How can statistical approaches be communicated more transparently to both experts and the broader audience?

In this episode, Oliver Keene and I delve into the realm of estimating treatment effects with continuous outcomes over time. We also delve into the article by Natey Ting, published in 2023, advocating for a reevaluation of estimation techniques. Ting's emphasis on the last observation analysis sparks a robust discussion as we dissect its applicability in the context of treatment policy and its potential limitations.

We also discuss the following key points: