When out-of-work-actors Raphael (Ivan Martin) and Dominic (Michael Godere) hustle a prominent New York producer into believing they've written a hot movie script, they have 10 days to deliver the goods or lose their last opportunity for a big break. Hoping to escape the bustle of New York City to write in peace, the duo head to the upstate country home of Dom's sister Gigi (Marisa Tomei). But their writer's retreat descends into bacchanalian romp when Gigi's hostile boyfriend Wayne (Sam Rockwell) and his younger brother Devon (Brian Geraghty) bring old flames and simmering grudges to a head for the group. As yearnings for love and familial dynamics threaten to derail their career-making opportunity, will Raph and Dom's friendship survive the creative process?

Tired of struggling to be an actress, Reese Holden (Zooey Deschanel) leaves New York and returns to her Michigan home. She has a cash advance from a book editor who wants to publish the love letters of Reese's parents. Reese has a strained relationship with her dad, a washed-up novelist, but she enters the household he shares with an ex-student and a shy friend who takes care of domestic matters.