A thrilling disaster film featuring an all-star cast. When a potentially deadly virus is unleashed on a transcontinental train by terrorists, the infected passengers must find a way to survive, even as outside forces conspire against them.

Ex-Green Beret and Vietnam vet John Rambo is sent on assignment back to Southeast Asia to uncover evidence of still missing POWs, and ends up with his hands full when he comes up against Vietnamese soldiers still guarding the camps, the Russian military that oversees them, and the American State department officials who apparently sent him there fully knowing that he'd be taking on a doomed mission.