A man who is traumatized by a car accident flourishes a friendship with a high-functioning autistic woman.

Best friends, Mia and Mel (Tiffany Haddish and Rose Byrne) are living their best lives, running their own cosmetics company until a villainous beauty mogul (Salma Hayek) conspires to steal it from under them. When her devious plan drives the besties apart, Mia and Mel learn that sticking together is the only way to turn the tables and take their company back. The beauty business is about to get ugly.

When Pete (Mark Wahlberg) and Ellie (Rose Byrne) decide to start a family, they stumble into the world of foster care adoption. They hope to take in one small child but when they meet three siblings, including a rebellious 15 year old girl (Isabela Moner), they find themselves speeding from zero to three kids overnight. Now, Pete and Ellie must hilariously try to learn the ropes of instant parenthood in the hopes of becoming a family. INSTANT FAMILY is inspired by the real events from the life of writer/director Sean Anders and also stars Octavia Spencer, Tig Notaro and Margo Martindale.