# 72 - Sleep & Cannabis

Matt introduces his series examining the complex relationship between sleep and cannabis, exploring both the historical context and contemporary scientific perspectives. The narrative begins with Dr. W.B. O'Shaughnessy's canine experiments in 1849, tracing the evolution to the foundational work on cannabis for sleep conducted by Drs. Clendinning and Bradbury. Despite anecdotal reports suggesting cannabis enhances sleep, the scenario is complicated by factors such as regulatory constraints, variable product quality, and the potential long-term health implications of cannabis usage.In discussing the impact of cannabis on sleep, Matt elucidates the interactions among THC, CBD, and the endocannabinoid system. Initial benefits may include improved sleep onset and efficiency, but chronic use is often associated with negative outcomes such as increased nocturnal awakenings and reduced sleep quality in the latter half of the night. Additionally, Matt explores the challenges associated with discontinuing cannabis use, including the risk of THC dependency for sleep induction, highlighting the necessity for evidence-based approaches and individualized decision-making in using cannabis as a sleep aid.Matt's analysis extends to the global context of cannabis consumption, advocating for well-informed choices amidst its growing popularity and the dynamic landscape of scientific research.Please be aware that Matt is not a medical professional, and the content of this podcast should not be regarded as medical advice or as prescriptive in any manner.This episode is sponsored by the Tim Ferriss Show, celebrating its ten-year anniversary with over 1 billion downloads since 2023. The show is renowned for Tim's profound interviews with a diverse range of guests—from Hollywood legends like Arnold Schwarzenegger and Jamie Foxx to lesser-known figures who have captivated Tim's attention—each episode is designed to offer deep insights and stimulate thoughtful discussions.  Tune in to Tim.blog or look for the Tim Ferriss Show today, available wherever you find your podcasts.The good people at InsideTracker are also one of the sponsors of this week's episode, and they are generously offering a special 25% off any one of their programs for anyone who uses the above link during the time window of this episode. InsideTracker is a personalized biometric platform that analyzes your blood and your DNA to better understand what's happening inside of you and offers suggestions regarding things that you can do to better try and adjust some of those numbers, optimize them, and, as a result, optimize you.Another sponsor of the show is AG1, a comprehensive nutritional drink trusted by thousands worldwide, including Matt! For nearly four years and counting, he has relied on AG1 to fuel his post-workout routine with its powerhouse blend of over 75 essential minerals, vitamins, probiotics, and prebiotics, meticulously crafted to support your daily nutritional needs. AG1 is registered and approved by the Therapeuti