Brain Natriuretic Peptide (BNP) Lab Values

Overview BNP Normal Value Range Pathophysiology Special considerations Lab value elevations Nursing Points General Normal value range 100 pg/mL Pathophysiology Increased pressure overload due to increased SVR or volume Ventricular stretching causes release of BNP into bloodstream BNP released to aid in stress due to overload by: Increases excretion of sodium in urine = natriuresis Sodium follows water Decreased intravascular volume Decreased workload on the heart = improved cardiac function Special considerations Lavender tube (EDTA) NT-proBNP may be requested instead Submit in serum separator tube (tiger top) Elevated lab values >100 pg/mL – heart failure likely The higher the value, the more likely the diagnosis of heart failure Assessment Assess patient for acute exacerbation of heart failure Lung sounds Oxygen status Need for supplemental oxygen Radiographic evaluation May need diagnostics for evaluation Echocardiogram can determine contractility function Therapeutic Management Treatment Treat heart failure Diurese Improve contractility Nursing Concepts Lab Values Perfusion