Using Antisense to Characterize Nonsense: A Mouse Model of Progranulin-Deficient Dementia

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In, discover the benefits and essential considerations when characterizing and using transgenic mouse models to test therapeutic approaches to treat neurodegenerative diseases.Plus, explore a knock-in mouse model of frontotemporal dementia that harbors a common mutation in the progranulin gene to test an antisense oligonucleotide (ASO)-based therapeutic strategy.Watch the full presentation here: https://events.bitesizebio.com/using-antisense-to-characterize/joinBrowse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/